Encryption: Disk based vs. file system vs. per file

Once your data is on disk, it's extremely important to continue to ensure its protection. I have personally used both Luks (https://access.redhat.com/knowledge/docs/en-US/Red_Hat_Enterprise_Linux/6/html/Security_Guide/sect-Security_Guide-LUKS_Disk_Encryption.html) and ecryptfs (https://access.redhat.com/knowledge/docs/en-US/Red_Hat_Enterprise_Linux/6/html/Storage_Administration_Guide/filesysnew-efs.html) in various configurations. I'm wondering what the overall experience has been with these two technologies, especially ecryptfs for on-disk based encryption.