Why aliases are not working in GNOME Terminal after setting in `.bash_profile`

Issue

• After setting up the aliases in .bash_profile file, they are not showing up in gnome terminal.

[root@example ~]# who am i
root pts/0        2013-12-06 21:51 (:0.0)
[root@example ~]# grep alias1 .bash_profile 
alias alias1='ls -a'
[root@example ~]# alias1
-bash: alias1: command not found
[root@example ~]# 

• However, the aliases are working in text consoles.