How do I map ttyUSB0 to ttyS0 while using USB to Serial convertor?

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Issue

I do not have serial port on my system and using USB to serial convertor on RHEL
Is there a way to map ttyUSB0 device to a standard serial port? for example, ttyS0
How do I get Linux to link a ttyUSB0 device to a standard serial port?

Environment

Red Hat Enterprise Linux 5
No serial port available on hardware
USB-to-serial adapter

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