How to configure JBoss datasource, system parameter isolation ?

Issue

• We want to one domain controller to manage multiple server (1 server/application) but we cannot isolate some parameter such as data source, system parameter setting for each server group under same profile. Please suggest me how to resolve this problem.
• We want to separate parameter by server group such as http-proxy system properties, DB data source, WSDL Host, etc.
• We don't want to have different configuration between servers in server group but we want to have different or isolate some configuration between server groups . We have plan to use one application per server group but some server group maybe are in same profile.