Is it possible to flush a multipath map when multipath -f reports that the map is in use?

Issue

• Unable to remove a multipath device in order to proceed with unmapping the LUN from the server.

• Attempting to flush a multipath map with "multipath -f" or "multipath -F" results in "map in use":

       # multipath -f mpath7
       mpath7: map in use
  

• Unable to remove the multipath device, even after unmapping the LUN from the server.