Are network tunables in ktune appropriate for my system?

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Issue

/etc/sysctl.ktune says: net.ipv4.tcp_mem = 8388608 12582912 16777216 Is this appropriate?
/etc/sysctl.ktune says: net.ipv4.udp_mem = 8388608 12582912 16777216 Is this appropriate?

Environment

Red Hat Enterprise Linux 5
ktune

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