10.2.4.6. The mod_perl Module

The configuration for mod_perl has been moved from httpd.conf into the file /etc/httpd/conf.d/perl.conf. For this file to be loaded, and hence for mod_perl to work, the statement Include conf.d/*.conf must be included in httpd.conf as described in Section 10.2.1.3, “Dynamic Shared Object (DSO) Support”.
Occurrences of Apache:: in httpd.conf must be replaced with ModPerl::. Additionally, the manner in which handlers are registered has been changed.
This is a sample Apache HTTP Server 1.3 mod_perl configuration: 
<Directory /var/www/perl>
    SetHandler perl-script
    PerlHandler Apache::Registry
    Options +ExecCGI
</Directory>
This is the equivalent mod_perl for Apache HTTP Server 2.0: 
<Directory /var/www/perl>
    SetHandler perl-script
    PerlResponseHandler ModPerl::Registry
    Options +ExecCGI
</Directory>
Most modules for mod_perl 1.x should work without modification with mod_perl 2.x. XS modules require recompilation and may require minor Makefile modifications.